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K1C40 Rabbit Polyclonal Antibody, 100ul Bottles |PTM:Phosphorylated by cyclin A/CDK2

SKU: 14677453044

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K1C40 Rabbit Polyclonal Antibody, 100ul Bottles |PTM:Phosphorylated by cyclin A/CDK2This gene encodes a member of the type I (acidic) keratin family which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments along with actin microfilaments and microtubules compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12 q21.

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Description

|PTM:Phosphorylated by cyclin A/CDK2

which has 77% amino acid sequence identity with mouse subunit VIc

but the full-length nature of some of these variants has not been fully characterized

A highly similar protein in mouse has both ferrireductase and cupric reductase activity

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

K1C40 Rabbit Polyclonal Antibody, 100ul Bottles |PTM:Phosphorylated by cyclin A/CDK2This gene encodes a member of the type I (acidic) keratin family which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments along with actin microfilaments and microtubules compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12 q21.

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