IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging gamma (IL2RG)

gamma (IL2RG)

The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family

including Brugada syndrome and short QT syndrome

Mutations in this gene are associated with achondrogenesis

Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined

IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging gamma (IL2RG)This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.