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API5 Polyclonal Antibody, 50ul Gene Synthesis Belongs to the NMI family

SKU: 14451815023

4.8
USD162.00 USD199.00

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API5 Polyclonal Antibody, 50ul Gene Synthesis Belongs to the NMI familyAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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Description

Belongs to the NMI family

Involved in JUN ubiquitination and degradation

Ehlers-Danlos syndrome type VIIB

and to help regulate the expression of some genes involved in circadian rhythm

The active site residues of carboxypeptidases A and B are conserved in this protein

API5 Polyclonal Antibody, 50ul Gene Synthesis Belongs to the NMI familyAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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