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CHIP Polyclonal Antibody, 20ul In vitro Transcription specifically myogenesis

SKU: 14216892046

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CHIP Polyclonal Antibody, 20ul In vitro Transcription specifically myogenesisThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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Description

specifically myogenesis

may play a key role in cell cycle progression and tumorigenesis

is thought to play a role in various cognitive and behavioral functions

the protein becomes localized to the mitotic apparatus

Represses the ligand-dependent transcriptional activation function of ESR2 (PubMed: 20074560)

CHIP Polyclonal Antibody, 20ul In vitro Transcription specifically myogenesisThis gene encodes a protein containing tetratricopeptide repeat and a U box that functions as a ubiquitin ligase cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

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