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RAGE Polyclonal Antibody, 50ul[BT-AP07639] Aspirating Pipets |tissue specificity:Expressed in fetal brain|

SKU: 14095839257

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RAGE Polyclonal Antibody, 50ul[BT-AP07639] Aspirating Pipets |tissue specificity:Expressed in fetal brain|The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non protein coding

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Description

|tissue specificity:Expressed in fetal brain| cartilage| retina| and adult gall bladder

Specifications: 5

but there is evidence that cells may not be able to engage in both activities at the same time

It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis

and participates in the MAP kinase-mediated signaling cascade

RAGE Polyclonal Antibody, 50ul[BT-AP07639] Aspirating Pipets |tissue specificity:Expressed in fetal brain|The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non protein coding

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