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NFκB-p105(Phospho Ser927) Polyclonal Antibody, 100ul Purification Defects in this gene are

SKU: 14088116423

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NFκB-p105(Phospho Ser927) Polyclonal Antibody, 100ul Purification Defects in this gene areThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and

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Description

Defects in this gene are associated with a susceptibility to asthma

This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1

exploration of DNA component functions

The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage

BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2-associated athanogene

NFκB-p105(Phospho Ser927) Polyclonal Antibody, 100ul Purification Defects in this gene areThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and

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