GIT2 Polyclonal Antibody, 50ul Molecular Biology Plays an important role in

Plays an important role in tumor suppression through p53/TP53 regulation

characterized by the backward flow of urine from the bladder into the ureters or the kidney

non-sterile

sterilized by irradiationto SAL 10^-6

Two similar genes are located nearby on chromosome 7q22 and a pseudogene is found on chromosome 7p13

GIT2 Polyclonal Antibody, 50ul Molecular Biology Plays an important role inGIT2 encodes a member of the GIT protein family, ARF GTPase activating protein GIT2, which interact with G protein coupled receptor kinases and possess ADP ribosylation factor (ARF) GTPase activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins.