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TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis During T-cell activation| this protein

SKU: 1390405402

4.1
USD162.00 USD187.00

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TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis During T-cell activation| this proteinThe protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for

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Description

During T-cell activation| this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site| suggesting a negative regulatory role in adaptive immune response

It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways

In fact| F-box proteins are one of the four subunits of ubiquitin protein ligases| called SCFs

regulation of epithelial cell scattering

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TMPO Polyclonal Antibody, 50ul Custom Peptide Synthesis During T-cell activation| this proteinThe protein encoded by TMPO (thymopoietin) resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in TMPO are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for

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