Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes This protein binds to DNA

This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE)

MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases

In spite of the gene family name similarity

see MIM 179508

as well as in T cell-dependent B cell proliferation and differentiation

Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes This protein binds to DNACABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding