Dkk-3 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos a complex required to maintain

a complex required to maintain the transcriptionally repressive state of many genes

skeletal muscle and at lower levels in brain and liver

It is predominantly expressed in the liver and secreted in plasma

This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene

tissue specificity:Expressed in normal mammary

Dkk-3 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos a complex required to maintainThis gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.