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NGB Polyclonal Antibody, 100ul Apoptosis & Autophagy inhibits VAV1 activation upon TCR

SKU: 13753106275

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NGB Polyclonal Antibody, 100ul Apoptosis & Autophagy inhibits VAV1 activation upon TCRThis gene encodes an oxygen binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic ischemic conditions.

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Description

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans

Mutations in this gene result in autosomal dominant hereditary thrombophilia

Alternative splicing results in three transcript variants which differ only in the 5' UTR

The diseases caused by mutations include amyloidotic polyneuropathy| euthyroid hyperthyroxinaemia| amyloidotic vitreous opacities| cardiomyopathy| oculoleptomeningeal amyloidosis| meningocerebrovascular amyloidosis| carpal tunnel syndrome| etc

NGB Polyclonal Antibody, 100ul Apoptosis & Autophagy inhibits VAV1 activation upon TCRThis gene encodes an oxygen binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic ischemic conditions.

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