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Rad21 Polyclonal Antibody, 50ul Organelle Studies Thrombospondin family members are adhesive

SKU: 13612263953

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Rad21 Polyclonal Antibody, 50ul Organelle Studies Thrombospondin family members are adhesiveThe protein encoded by RAD21 (RAD21 cohesin complex component) is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region

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Description

Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions

subunit:Binds to the death domain of TNFRSF6 and TRADD

and these interactions affect the rate of transcription initiation

subcellular location:Located on plasma membrane of neuroblastoma NMB7 cells

These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion

Rad21 Polyclonal Antibody, 50ul Organelle Studies Thrombospondin family members are adhesiveThe protein encoded by RAD21 (RAD21 cohesin complex component) is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region

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