HMGB3 Rabbit Polyclonal Antibody, 50ul Cell Culture Flasks a transcriptional regulator of immunoglobulin

a transcriptional regulator of immunoglobulin genes

It is responsible for sulfation of GalNAc on luteinizing hormone (LH)

and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa

Has a microtubule plus end-directed motility

The gene is deleted in Williams-Beuren syndrome| a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11

HMGB3 Rabbit Polyclonal Antibody, 50ul Cell Culture Flasks a transcriptional regulator of immunoglobulinThis gene encodes a member of a family of proteins containing one or more high mobility group DNA binding motifs. The encoded protein plays an important role in maintaining stem cell populations and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants.