Gab 2(Phospho Tyr643) Polyclonal Antibody, 20ul Live Cell Imaging Cleaves caspase-1

Cleaves caspase-1

This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

Because it binds Shc independent of stimulation and Grb2 after stimulation

subcellular location:Nuclear following IFN treatment

It is associated with CREM and confers a powerful transcriptional activation function

Gab 2(Phospho Tyr643) Polyclonal Antibody, 20ul Live Cell Imaging Cleaves caspase-1This gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in