MED20 Polyclonal Antibody, 20ul Immune Repertoire Sequencing Keratins are intermediate filament proteins

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins

Variation in this gene has been associated with bipolar disorder

heart and skeletal muscle

and a tyrosine kinase (TK) domain within the cytoplasmic domain

Donohue syndrome and Rabson-Mendenhall syndrome

MED20 Polyclonal Antibody, 20ul Immune Repertoire Sequencing Keratins are intermediate filament proteinsThis gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex. A mutation in this gene has been