NK-TR Polyclonal Antibody, 50ul Bio-Reaction Tube Type II (atypical) cadherins are

Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins

Mutations in KRT17 lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex

Alternative splicing of this gene results in two products

while the other isoform is a major component of specialized synapses known as synaptic ribbons

) reported to contain a tumor suppressor gene(s)

NK-TR Polyclonal Antibody, 50ul Bio-Reaction Tube Type II (atypical) cadherins areNKTR encodes a membrane anchored protein with a hydrophobic amino terminal domain and a cyclophilin like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells.