Shc(Phospho Tyr427) Polyclonal Antibody, 100ul Monoclonal Antibody Preparation which may be partly responsible

which may be partly responsible for the protection against cell death

YEATS4 has been shown to be amplified in tumors

and has been shown to be a major component required for serum-dependent melanoma cell growth

The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6

subunit:Part of a decapping complex consisting of DCP1A

Shc(Phospho Tyr427) Polyclonal Antibody, 100ul Monoclonal Antibody Preparation which may be partly responsibleThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.