B2L13 Polyclonal Antibody, 100ul Cellular Function Assays DPYSL2 encodes a member of

DPYSL2 encodes a member of the collapsin response mediator protein family

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified

Members of this family have been identified in plants| vertebrates| and invertebrates| and they share a conserved N-terminal transcription activation region and a conserved C-terminal DNA and phosphatidylinositol-phosphate binding region

The interaction of this protein with TRADD

B2L13 Polyclonal Antibody, 100ul Cellular Function Assays DPYSL2 encodes a member ofThis gene encodes a mitochondrially localized protein with conserved B cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene.