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SP-100 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The receptor is primarily located

SKU: 12546680966

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SP-100 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The receptor is primarily locatedSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one

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Description

The receptor is primarily located in the anterior pituitary

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum

selectin P ligand plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins

ADAM10 (ADAM metallopeptidase domain 10) encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin

The encoded protein is associated with the calyx of spermatozoa and spermatids

SP-100 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The receptor is primarily locatedSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one

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