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Caspase-9 Polyclonal Antibody, 50ul[BT-AP01213] RNA Synthesis Studies of the Drosophila counterpart

SKU: 12375519759

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SEK162.00 SEK208.00

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Caspase-9 Polyclonal Antibody, 50ul[BT-AP01213] RNA Synthesis Studies of the Drosophila counterpartCASP9 (caspase 9) encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the

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Description

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

11) to NA mononucleotide (NaMN)| which is then converted to NA adenine dinucleotide (NaAD)| and finally to nicotinamide adenine dinucleotide (NAD)| which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al

This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues

This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex

but with distinct 3' ends

Caspase-9 Polyclonal Antibody, 50ul[BT-AP01213] RNA Synthesis Studies of the Drosophila counterpartCASP9 (caspase 9) encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the

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