Raf-1 Polyclonal Antibody, 100ul[BT-AP13533] Polyclonal Antibodies Individually blister packed in peel-to-open

Individually blister packed in peel-to-open paper/plastic and plastic/plastic wrappers with printed lot No

These variants encode different isoforms| which are differentially expressed and have different kinase activities

Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms

Contains 1 CCHC-type zinc finger

The growth factor receptor bound protein 2 encoded by GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains

Raf-1 Polyclonal Antibody, 100ul[BT-AP13533] Polyclonal Antibodies Individually blister packed in peel-to-openThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.