Akt Polyclonal Antibody, 100ul[BT-AP00336] Recombinant Protein Expression The encoded protein is involved

The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes

and it is part of a duplicated region of chromosome 1p36

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner

MIM 176730) (Olbrot et al

This gene could be involved in the histone hyperacetylation pathway

Akt Polyclonal Antibody, 100ul[BT-AP00336] Recombinant Protein Expression The encoded protein is involvedThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a