PRGC2 Rabbit Polyclonal Antibody, 50ul Capsule Filter Genome-wide association studies in human

Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity

and is thought to be involved in mesoderm segmentation

including those encoding very large proteins

An apparent pseudogene of this gene is present on chromosome 8

This gene is expressed primarily in B-lymphoid and myeloid cell lines

PRGC2 Rabbit Polyclonal Antibody, 50ul Capsule Filter Genome-wide association studies in humanThe protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors including estrogen receptor alpha nuclear respiratory factor 1 and glucocorticoid receptor. The encoded protein may be involved in fat oxidation non oxidative glucose metabolism and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene