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CD6 Polyclonal Antibody, 50ul[BT-AP01552] ROS/Nitric Oxide Detection This isoform (alpha 1) is

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CD6 Polyclonal Antibody, 50ul[BT-AP01552] ROS/Nitric Oxide Detection This isoform (alpha 1) isLILRB2 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B2 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). The receptor is expressed on immune cells

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Description

This isoform (alpha 1) is expressed in brain| placenta| lung| liver| kidney| and pancreas| and the other isoform (alpha 2) is expressed in brain| heart and skeletal muscle

Mutations in or deletions of the gene lead to growth hormone deficiency and short stature

Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS)

human papillomavirus type 16 L2 mRNA

Mutations in this gene are a cause of spastic ataxia 2

CD6 Polyclonal Antibody, 50ul[BT-AP01552] ROS/Nitric Oxide Detection This isoform (alpha 1) isLILRB2 is a member of the leukocyte immunoglobulin like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B2 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine based inhibitory motifs (ITIMs). The receptor is expressed on immune cells

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