AGFG1 Polyclonal Antibody, 20ul Pathway and Network Analysis Multiple pseudogenes exist on chromosomes

Multiple pseudogenes exist on chromosomes 5

a relatively common human disorder with phenotypic features including cleft palate

This gene encodes one of the catalytic subunits of protein kinase A| which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits| in its inactive form

Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure

GPR135 (G Protein-Coupled Receptor 135) is a Protein Coding gene

AGFG1 Polyclonal Antibody, 20ul Pathway and Network Analysis Multiple pseudogenes exist on chromosomesThe protein encoded by this gene is related to nucleoporins a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target and is required for the nuclear export of Rev directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.