NALP2 Polyclonal Antibody, 100ul Cellular Function Assays one of the three alpha

one of the three alpha chains of type VI collagen

PPP4C-PPP4R2-PPP4R3A

The N-terminal half of this protein is required for its centrosome localization and for its multimerization

and also play critical roles in maintaining cell polarity and signal transductions

It is involved in energy metabolism| neuronal cell development| and body pattern formation

NALP2 Polyclonal Antibody, 100ul Cellular Function Assays one of the three alphaNALP proteins, such as NALP2, are characterized by an N terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase 1 (CASP1; MIM 147678) by Toll like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003