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RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging One of the isoforms (CXCR3-B)

SKU: 11337658741

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RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging One of the isoforms (CXCR3-B)RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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Description

One of the isoforms (CXCR3-B) shows high affinity binding to chemokine

They play a critical role in muscle differentiation

CYP3A43 (cytochrome P450 family 3 subfamily A member 43) encodes a member of the cytochrome P450 superfamily of enzymes

This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA)

Involved in embryogenesis and hematopoiesis Diseases associated with HLX include ovarian endodermal sinus tumor and ovarian primitive germ cell tumor

RUNX2 Polyclonal Antibody, 20ul[BT-AP08060] Live Cell Imaging One of the isoforms (CXCR3-B)RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA binding domain. Runt related transcription factor 2 is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions

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