TEF-1 Polyclonal Antibody, 100ul In vitro Assessment enzyme regulation:Regulated by guanine nucleotide

enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP

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monocytes and macrophages

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

Mutations in this gene have been associated with Andersen syndrome

TEF-1 Polyclonal Antibody, 100ul In vitro Assessment enzyme regulation:Regulated by guanine nucleotideTEAD1 (TEA domain transcription factor 1) encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in TEAD1 cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full length natures have not been experimentally