HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation This gene encodes an enzyme

This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis| which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI)

Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D| and expression of this gene may be a prognostic indicator for several types of cancer

|PTM:Isoform 4 is phosphorylated by PKA

and it is essential for lactation

Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections

HNK-1ST Polyclonal Antibody, 100ul Drug Development and Evaluation This gene encodes an enzymeCarbohydrate sulfotransferase 10 encoded by CHST10 transfers sulfate to the C 3 hydroxyl of terminal glucuronic acid of protein and lipid linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer 1 (HNK 1) glycan; HNK 1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.