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PKR(Phospho Thr258) Polyclonal Antibody, 20ul Drug Development and Evaluation NOC2L represents a novel HDAC-independent

SKU: 1107649107

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PKR(Phospho Thr258) Polyclonal Antibody, 20ul Drug Development and Evaluation NOC2L represents a novel HDAC-independentThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al

Mutations in SLC5A2 are associated with renal glucosuria

It has no cross-reaction to other GABARAP protein

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

Epsin 2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery

PKR(Phospho Thr258) Polyclonal Antibody, 20ul Drug Development and Evaluation NOC2L represents a novel HDAC-independentThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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