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ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment Several alternatively spliced transcript variants

SKU: 10962770261

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ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment Several alternatively spliced transcript variantsThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of

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Description

Several alternatively spliced transcript variants of FKRP have been described

and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC)

The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85

This protein contains an actin filament-binding domain| which together with its Dbl homology domain and one of its pleckstrin homology domains| can form microspikes

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ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment Several alternatively spliced transcript variantsThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of

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