ERCC4 Polyclonal Antibody, 100ul Vortex Mixer Contains 3 GoLoco domains

Contains 3 GoLoco domains

The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs

The molecular weight of non-phosphorylated FRS2 is 57-68 kDa

Mutations in this gene result in congenital disorder of glycosylation type If

This protein also binds Zn2+ and Cu2+

ERCC4 Polyclonal Antibody, 100ul Vortex Mixer Contains 3 GoLoco domainsERCC excision repair 4, endonuclease catalytic subunit encoded by ERCC4 forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP F), or xeroderma pigmentosum VI (XP6).