p95/NBS1(Phospho-Ser343) Rabbit Polyclonal Antibody, 50ul Culture Media which is composed of a

which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain

Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy

Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome

GO annotations related to this gene include actin binding and WW domain binding

isolated 8

p95/NBS1(Phospho-Ser343) Rabbit Polyclonal Antibody, 50ul Culture Media which is composed of aMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint