N2DL3 Polyclonal Antibody, 50ul Cell Screening and Imaging and pancreas (Alanentalo et al

and pancreas (Alanentalo et al

This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members

and thus may function as a regulator of Rho signaling pathways

A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10

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N2DL3 Polyclonal Antibody, 50ul Cell Screening and Imaging and pancreas (Alanentalo et alThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.