EpoR Polyclonal Antibody, 50ul[BT-AP03025] Cytokines Multiple alternatively spliced transcript variants
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EpoR Polyclonal Antibody, 50ul[BT-AP03025] Cytokines Multiple alternatively spliced transcript variantsEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce
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