NNT-1 Polyclonal Antibody, 100ul Serum Mutations in this gene have

Mutations in this gene have been associated with congenital insensitivity to pain

Can form homodimers or heterodimers with other AP-2 family members

This gene is regulated by oxygen tension

which stimulates glucose-induced insulin secretion

The encoded protein may be involved in regulating intracellular trafficking

NNT-1 Polyclonal Antibody, 100ul Serum Mutations in this gene haveThis gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex, and activates the Jak STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with