DNA Ligase III Polyclonal Antibody, 50ul Endonucleases & Exonucleases a proposed oncogene whose activity

a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization

As the encoded protein has not been detected

plays a role in chromosome assembly and segregation during mitosis

a common recessive X-linked coagulation disorder

The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells

DNA Ligase III Polyclonal Antibody, 50ul Endonucleases & Exonucleases a proposed oncogene whose activityLIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon