RHEB Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification MOB kinase activator 3B encoded

MOB kinase activator 3B encoded by MOB3B shares similarity with the yeast Mob1 protein

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism

This gene encodes a conserved member of the trypsin family of serine proteases

Mutations or deletions in this gene have been shown to result in pancreatic cancer

RHEB Polyclonal Antibody, 100ul DNA/RNA Isolation & Purification MOB kinase activator 3B encodedRHEB (Ras homolog enriched in brain) is a member of the small GTPase superfamily and encodes a lipid anchored, cell membrane protein with five repeats of the RAS related GTP binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin TOR S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP bound form and a GTP bound form, and farnesylation of the protein is