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ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator Alternate splicing of EPN2 results

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ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator Alternate splicing of EPN2 resultsApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

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Description

Alternate splicing of EPN2 results in multiple transcript variants encoding different isoforms

which is necessary for osmolytic pore formation

Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein

This protein (tumor necrosis factor superfamily member 13) is a ligand for TNFRSF17/BCMA

The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions

ApoA-IV Monoclonal Antibody, 50ul[BT-MCA0167] Rotator Alternate splicing of EPN2 resultsApoliprotein (apo) A IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396 residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A IV is a potent activator of lecithin cholesterol

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