Tie-2 Polyclonal Antibody, 50ul[BT-AP09017] Immune Repertoire Sequencing Harlequin icthyosis

Harlequin icthyosis

Mutations in this gene may be associated with type 2 diabetes in human patients

Mutations in this gene are a cause of spastic ataxia 2| autosomal recessive

The von Hippel-Lindau tumor suppressor protein binds to elongins B and C

ZNF280C (zinc finger protein 280C) encodes a member of the zinc finger domain-containing protein family

Tie-2 Polyclonal Antibody, 50ul[BT-AP09017] Immune Repertoire Sequencing Harlequin icthyosisTEK (TEK receptor tyrosine kinase) encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in TEK