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Common side effects include nausea, vomiting, diarrhea, constipation, headaches and injection site reactions (redness, swelling, irritation)

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the product thus obtained presents the 1H-NMR spectra shown in FIG

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First, we monitored the reduction of NADP + to NADPH in the isocitrate dehydrogenase-catalysed reaction from isocitrate to -ketoglutarate (Supplementary Fig