Mouse Dickkopf-3, DKK3 ELISA Kit, 96T Nucleic Acid Amplification 100% integrity test
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Mouse Dickkopf-3, DKK3 ELISA Kit, 96T Nucleic Acid Amplification 100% integrity testAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone
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