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49,54 In addition, the large size of mRNA and its susceptibility to degradation by nucleases result in low cellular uptake, further limiting its application

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Alternative to supplementation of precursors, as described in the NAD + and precursors supplementation section, it is possible to administer NAD + itself through intravenous infusions 66,116,117

Xu J, Dun J, Yang J, Zhang J, Lin Q, Huang M, Ji F, Huang L, You X, Lin Y (2020) Letrozole Rat model mimics human polycystic ovarian syndrome and changes in insulin signal pathways

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