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Synuclein- Alpha Polyclonal Antibody, 100ul[BT-AP08726] Recombinant Ab Production Alternative splicing results in multiple

SKU: 51004938197

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Synuclein- Alpha Polyclonal Antibody, 100ul[BT-AP08726] Recombinant Ab Production Alternative splicing results in multipleAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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Description

Alternative splicing results in multiple transcript variants| at least one of which encodes an isoform that is proteolytically processed

Polymorphisms in this gene may be associated with systemic sclerosis

which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors

Contains 6 LRR (leucine-rich) repeats

and gamma subunits that assemble through a coiled-coil domain

Synuclein- Alpha Polyclonal Antibody, 100ul[BT-AP08726] Recombinant Ab Production Alternative splicing results in multipleAlpha synuclein is a member of the synuclein family, which also includes beta and gamma synuclein. Synucleins are abundantly expressed in the brain and alpha and beta synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with

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