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Recommended Follow-Up Schedule Week 4: Assess tolerability, review injection technique, evaluate early response Monthly during escalation: Monitor weight, vital signs, side effects, and medication adherence at each dose increase Every 3 months at maintenance: Weight, body composition, laboratory studies (metabolic panel, HbA1c, lipid panel), assessment of comorbidity improvement Annually: Comprehensive reassessment including updated laboratory workup and treatment plan review Treatment Response Assessment Semaglutide training for physicians should establish criteria for evaluating treatment success