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Patients taking other psychiatric medications, particularly those that interact with serotonin or dopamine systems, should discuss semaglutide use with both their mental health provider and weight loss clinician

Energy availability is lower, recovery capacity is often reduced, and the priority shifts from "burn more calories" to "send the strongest possible signal to preserve muscle" with the least metabolic cost

MASLD is a heterogeneous disease influenced by genetic, metabolic, and environmental factors

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