SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein localizes to

The encoded protein localizes to centrosomes and microtubules| and associates with the GTP-activated forms of Ras| Rap1| and several other Ras-like small GTPases

and the nuclear-encoded subunits may function in the regulation and assembly of the complex

Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease

This gene encodes an RNA-binding phosphoprotein that is part of the MEX3 (muscle excess 3) family of translational regulators

Potein phosphatase 2 regulatory subunit B''gamma is localized to both nuclear and cytoplasmic regions depending on cell cycle phase

SIM1 Rabbit Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein localizes toSIM1 and SIM2 genes are Drosophila single minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull