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This article was financially supported by National Institutes of Health Public Health Service grants R01 HL144790, R01 HL151493, R01 AI145813, R01 AI169687, R01 HL151769, and R01 HL159804 (OA)

It has also been shown that ACE-inhibiting peptides stop the activity of the ACE-I enzyme in the renin-angiotensin-aldosterone system, thereby preventing the conversion of angiotensin I, a vasodilator decapeptide, into angiotensin II, a vasoconstrictive octapeptide

Since BPC-157 has not been thoroughly tested in humans, its safety profile remains unknown

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