Dkk-3 Polyclonal Antibody, 20ul Capsule Filter and synaptic membranes from the

and synaptic membranes from the CNS

The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon

This gene product stimulates the motility of tumor cells and has angiogenic properties

This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response

each with a specific pattern of ligand binding and tissue distribution

Dkk-3 Polyclonal Antibody, 20ul Capsule Filter and synaptic membranes from theDKK3 encodes dickkopf WNT signaling pathway inhibitor 3 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of DKK3 is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.