SART3 Polyclonal Antibody, 20ul Reagent Reservoirs Constitutive) is a Protein Coding

Constitutive) is a Protein Coding gene

targeting specific proteins for ubiquitin-mediated proteolysis

|tissue specificity:Detected in spleen and thyroid| and at lower levels in kidney| brain| lung and pancreas

Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility

Alternatively spliced transcript variants that encode different isoforms have been observed for this gene

SART3 Polyclonal Antibody, 20ul Reagent Reservoirs Constitutive) is a Protein CodingThe protein encoded by this gene is an RNA binding nuclear protein that is a tumor rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA A24 restricted and tumor specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV 1 gene expression and viral replication. It also associates transiently with U6 and U4 U6 snRNPs